Document Detail


Thrombolytic therapy is indicated for patients over 75 years of age with st-elevation acute myocardial infarction: antagonist viewpoint.
MedLine Citation:
PMID:  14610382     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
From the available data, one cannot conclude whether thrombolytic therapy is beneficial or detrimental in patients older than age 75 years with acute myocardial infarction. Data favor the use of primary percutaneous transluminal coronary angioplasty rather than thrombolysis in eligible patients older than age 75 years with acute myocardial infarction to reduce mortality, recurrent myocardial infarction, stroke, and intracranial hemorrhage. High-risk elderly patients with acute myocardial infarction, such as those with a large anterior myocardial infarction complicated by heart failure and hypotension, those with persistent ischemic pain or marked ST-segment changes, those with hemodynamic instability, and those at high risk for stroke or bleeding complications, should, especially, be treated with percutaneous transluminal coronary angioplasty.
Authors:
Wilbert S Aronow
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of geriatric cardiology     Volume:  12     ISSN:  1076-7460     ISO Abbreviation:  Am J Geriatr Cardiol     Publication Date:    2003 Nov-Dec
Date Detail:
Created Date:  2003-11-11     Completed Date:  2004-04-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9215283     Medline TA:  Am J Geriatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  348-50     Citation Subset:  IM    
Affiliation:
The Cardiology Division, New York Medical College, Valhalla, NY,USA. WSAronow@aol.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Angioplasty, Transluminal, Percutaneous Coronary*
Fibrinolytic Agents / therapeutic use
Humans
Myocardial Infarction / drug therapy*,  therapy
Risk Factors
Streptokinase / therapeutic use
Thrombolytic Therapy / adverse effects*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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