Document Detail

Thrombolysis versus primary percutaneous transluminal coronary angioplasty for acute myocardial infarction.
MedLine Citation:
PMID:  10348969     Owner:  NLM     Status:  MEDLINE    
For the patient with acute myocardial infarction (MI), both primary percutaneous transluminal coronary angioplasty (PTCA) and intravenous thrombolytic therapy are effective in restoring antegrade coronary blood flow, improving left ventricular systolic function, and reducing mortality. Primary PTCA is effective when performed quickly by experienced operators. It is the preferred therapy in the patient a) with a contraindication to thrombolytic therapy, b) aged 70 years or older, and c) in whom thrombolytic therapy is likely to be ineffective (ie, the patient with cardiogenic shock). Thrombolytic therapy is widely available and can be given quickly and easily. As a result, it remains the treatment of choice for most patients with acute MI. The goal of therapy for the patient with acute MI is the rapid and sustained restoration of coronary blood flow. For the individual patient, the better therapy-primary PTCA or thrombolytic therapy-is the one that can be given more safely and expeditiously.
R A Lange; J E Cigarroa; L D Hillis
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Cardiology in review     Volume:  7     ISSN:  1061-5377     ISO Abbreviation:  Cardiol Rev     Publication Date:    1999 Mar-Apr
Date Detail:
Created Date:  1999-12-02     Completed Date:  1999-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9304686     Medline TA:  Cardiol Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  77-82     Citation Subset:  IM    
University of Texas Southwestern Medical Center, Dallas, Texas 75235-9047, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Circulation / drug effects
Myocardial Infarction / mortality,  therapy*
Survival Rate
Thrombolytic Therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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