Document Detail

Thrombolysis of palmar and digital arterial thrombosis by intra-arterial Thrombolysin.
MedLine Citation:
PMID:  139418     Owner:  NLM     Status:  MEDLINE    
In nine patients, one with bilateral findings, impending gangrene of the hand due to thrombosis of the palmar arch or digital arteries did not respond to current surgical methods or to common nonsurgical measures and was treated by intra-arterial thrombolysin. The author's recommended diagnostic arteriography, direct surgical treatment, if indicated, and specific coagulation studies. Thrombolysin was given by perfusion at a rate of 100,000 U. per hour. Careful monitoring of the clotting process prevented any significant bleeding and excellent recovery occurred in eight hands and there was a good result in two.
M M Kartchner; W C Wilcox
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of hand surgery     Volume:  1     ISSN:  0363-5023     ISO Abbreviation:  J Hand Surg Am     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1977-05-12     Completed Date:  1977-05-12     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7609631     Medline TA:  J Hand Surg Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  67-74     Citation Subset:  IM    
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MeSH Terms
Drug Combinations
Fibrinolysin / administration & dosage*,  therapeutic use
Fingers / blood supply*
Hand / blood supply*
Injections, Intra-Arterial
Middle Aged
Plasminogen / administration & dosage*,  therapeutic use
Streptokinase / administration & dosage*,  therapeutic use
Thrombosis / drug therapy*
Reg. No./Substance:
0/Drug Combinations; 9001-91-6/Plasminogen; EC 3.4.-/Streptokinase; EC

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