Document Detail


Thrombolysis in the management of acute myocardial infarction. Current status and future perspectives.
MedLine Citation:
PMID:  9973856     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The optimal thrombolytic regimen is front-loaded alteplase with vigorous heparinization: the reperfusion treatment that leads to the lowest 30 day mortality. The role of heparin alone or in combination with thrombolysis is still unclear. Hirudin does not provide benefit over heparin, as we have seen in the trials, and glycoprotein blockers are promising in PTCA. They can also be effective in unstable angina and possibly in acute myocardial infarction.
Authors:
F Verheugt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology     Volume:  17     ISSN:  0870-2551     ISO Abbreviation:  Rev Port Cardiol     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-03-05     Completed Date:  1999-03-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8710716     Medline TA:  Rev Port Cardiol     Country:  PORTUGAL    
Other Details:
Languages:  eng     Pagination:  959-65     Citation Subset:  IM    
Affiliation:
Department of Cardiology, University Hospital Nijmegen, The Netherlands
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MeSH Terms
Descriptor/Qualifier:
Clinical Trials as Topic
Drug Therapy, Combination
Fibrinolytic Agents / administration & dosage*
Heparin / administration & dosage
Humans
Myocardial Infarction / drug therapy*
Recurrence
Thrombolytic Therapy / trends*
Time Factors
Tissue Plasminogen Activator / administration & dosage*
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; 9005-49-6/Heparin; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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