Document Detail

Thrombolysis and angioplasty of chronic iliac artery occlusions.
MedLine Citation:
PMID:  8770845     Owner:  NLM     Status:  MEDLINE    
The role of percutaneous angioplasty in the management of chronic iliac artery occlusions is controversial. This article reviews 7 years of experience in treating patients with complete chronic iliac artery occlusions (n = 99) by using thrombolysis and angioplasty. Patients were not excluded due to age or length of the lesion, or severity of underlying peripheral vascular disease. Thrombolysis was conducted with infusion of urokinase at a rate of 60,000-80,000 IU/h for 24 hours. Angioplasty was then performed irrespective of the results of thrombolysis. Seventy-nine percent of patients responded to urokinase, with complete lysis achieved in 55%. Angioplasty was successful in all patients with complete thrombolysis and in 88% of those with partial thrombolysis. The overall success rate was 86%, and more than 80% of surviving patients were symptom free at 5 years. There were seven complications, and the 30-day mortality rate was 2%. Our present results confirm the efficacy of thrombolysis/angioplasty for chronic arterial occlusions.
A Motarjeme; G I Gordon; K Bodenhagen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  6     ISSN:  1051-0443     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:    1995 Nov-Dec
Date Detail:
Created Date:  1996-09-26     Completed Date:  1996-09-26     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  66S-72S     Citation Subset:  IM    
Midwest Vascular Institute, Downers Grove, IL 60515, USA.
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MeSH Terms
Aged, 80 and over
Angioplasty, Balloon / instrumentation*
Arterial Occlusive Diseases / drug therapy*
Combined Modality Therapy
Dose-Response Relationship, Drug
Drug Administration Schedule
Fibrinolytic Agents / administration & dosage
Follow-Up Studies
Iliac Artery*
Middle Aged
Thrombolytic Therapy / instrumentation*
Treatment Outcome
Urokinase-Type Plasminogen Activator / administration & dosage
Reg. No./Substance:
0/Fibrinolytic Agents; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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