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Thrombolysis for acute ischemic stroke.
MedLine Citation:
PMID:  19849662     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
In the last decennium, thrombolytic therapy has changed the management of acute ischemic stroke. Randomized clinical studies have demonstrated that intravenous thrombolysis with tissue plasminogen activator improves functional outcomes. Recently the time window for intravenous thrombolysis has been extended from 3 to 4.5 hours after stroke onset, which will allow more stroke patients to benefit from this treatment. Currently several studies are investigating how to improve recanalization rates of thrombolytic therapy. In this review several aspects of intravenous and intra-arterial thrombolysis are discussed.
Authors:
M Uyttenboogaart; J De Keyser; G J Luijckx
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current topics in medicinal chemistry     Volume:  9     ISSN:  1873-4294     ISO Abbreviation:  Curr Top Med Chem     Publication Date:  2009  
Date Detail:
Created Date:  2009-11-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101119673     Medline TA:  Curr Top Med Chem     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1285-90     Citation Subset:  IM    
Affiliation:
Department of Neurology, University Medical Center Groningen, University of Groningen, the Netherlands. m.uyttenboogaart@neuro.umcg.nl
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