| Thrombogenicity of pulmonary-artery catheters. | |
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MedLine Citation:
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PMID: 3558936 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The thrombogenicity of heparin-bonded and non-heparin-bonded pulmonary-artery catheters was compared by means of pull-out phlebography in a prospective, randomized clinical study of 20 patients in an intensive care unit (ICU). The duration of catheterization averaged 47.4 +/- 4.1 h in the heparin-bonded group (10 patients) and 45.7 +/- 7.1 h in the non-heparin-bonded (10 patients). Age, clinical diagnosis, mean time required to obtain a stable wedge position, heparin dose administered and clotting indices were comparable between the groups. There was no statistically significant difference in the length of formed thrombi (2.3 +/- 1.89 vs 5.88 +/- 4.62 cm) or frequency of thrombus formation between the groups. The thrombi originated and propagated from the puncture site. They were mural proximally and formed sleeves in the superior vena cava. Several sleeves stripped off on withdrawal of the catheter. Protection from thrombosis offered by heparin bonding of pulmonary-artery catheters should, therefore, not be overestimated--at least not in long-term catheterization of ICU patients. |
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Authors:
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P Mollenholt; I Eriksson; T Andersson |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Intensive care medicine Volume: 13 ISSN: 0342-4642 ISO Abbreviation: Intensive Care Med Publication Date: 1987 |
Date Detail:
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Created Date: 1987-05-06 Completed Date: 1987-05-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7704851 Medline TA: Intensive Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 57-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Catheters, Indwelling / adverse effects* Female Heparin / administration & dosage Humans Male Middle Aged Phlebography Prospective Studies Pulmonary Artery* / radiography Random Allocation Thrombosis / etiology, prevention & control* |
| Chemical | |
Reg. No./Substance:
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9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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