Document Detail


Thromboembolism complicating thrombin injection of femoral artery pseudoaneurysm: management with intraarterial thrombolysis.
MedLine Citation:
PMID:  11340145     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ultrasound (US)-guided compression of pseudoaneurysms is being rapidly replaced by US-guided percutaneous treatment with thrombin injection because of the less intensive nature of this procedure. Thromboembolism after percutaneous treatment with thrombin injection is rare and has been described in brachial artery pseudoaneurysms. These were managed with intravenous administration of heparin and surgical thrombectomy. In this report, the authors describe thromboembolic complication of thrombin injection after treatment of a femoral artery pseudoaneurysm. This was managed by intraarterial thrombolysis with use of recombinant tissue plasminogen activator (rt-PA) with resolution of all major occlusive changes. A lower dose of thrombin injection and frequent postprocedural monitoring of distal pulses is recommended.
Authors:
S Sadiq; W Ibrahim
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  12     ISSN:  1051-0443     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-07     Completed Date:  2001-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  633-6     Citation Subset:  IM    
Affiliation:
Department of Radiology, St. Joseph Mercy Hospital, 44405 Woodward Ave., Pontiac, Michigan 48341, USA. sadiq5@mediaone.net
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MeSH Terms
Descriptor/Qualifier:
Aged
Aneurysm, False / drug therapy*
Female
Femoral Artery*
Fibrinolytic Agents / therapeutic use*
Humans
Thrombin / administration & dosage,  adverse effects*
Thromboembolism / drug therapy*,  etiology*
Thrombolytic Therapy / methods*
Tissue Plasminogen Activator / therapeutic use*
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; EC 3.4.21.5/Thrombin; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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