| Thromboembolic prophylaxis in orthopedic surgery using dabigatran: an oral direct thrombin inhibitor. | |
| | |
MedLine Citation:
|
PMID: 22458575 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Dabigatran etexilate is a direct thrombin inhibitor that has been in clinical use for the prevention and treatment of venous and arterial thrombosis. Dabigatran allows for oral administration, has a rapid onset of action and has a predictable anticoagulant effect. Studies in healthy volunteers and in patients undergoing orthopedic surgery indicate that dabigatran has a predictable pharmacokinetic profile, allowing for a fixed-dose regimen without the need for coagulation monitoring. Dabigatran is approved in the EU and Canada for prophylaxis of thromboembolism in patients undergoing total hip and knee arthroplasties. The focus of this article is on the clinical data of using dabigatran as venous thromboprophylaxis in orthopedic surgery patients. |
| | |
Authors:
|
Reed Garza; Michael H Huo |
Related Documents
:
|
16290895 - Using qualitative evaluation in a feasibility study to improve and refine a complementa... 4015375 - Review of gunshot wounds in dayton, ohio. demographics, anatomic areas, results, and co... 20002765 - Impact of medicare part d on medicare-medicaid dual-eligible beneficiaries' prescriptio... 15260515 - Cost effectiveness of memantine in alzheimer's disease: an analysis based on a probabil... 1792875 - Results and complications of the lcs (low contact stress) knee system. 16183005 - Why now? timing and circumstances of hastened deaths. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Expert review of cardiovascular therapy Volume: 10 ISSN: 1744-8344 ISO Abbreviation: Expert Rev Cardiovasc Ther Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-03-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101182328 Medline TA: Expert Rev Cardiovasc Ther Country: England |
Other Details:
|
Languages: eng Pagination: 423-7 Citation Subset: IM |
Affiliation:
|
Department of Orthopedic Surgery, University of Texas Southwestern Medical Center, 1801 Inwood Road, Dallas, TX 75390-8883, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bivalirudin for primary percutaneous coronary intervention in acute myocardial infarction: the HORIZ...
Next Document: No country for old stents? Improving long-term patient outcomes with biodegradable polymer drug-elut...