| Thromboembolic disease after total knee replacement: experience of 5100 cases. | |
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MedLine Citation:
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PMID: 19008109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to quantify the incidence and timing of venous thromboembolic events (VTE) after total knee replacement (TKR). Data from 5100 consecutive TKRs performed over 10 years were prospectively collected. Cases were reviewed to identify thromboprophylaxis given, the diagnosis of VTE, treatment and adverse outcomes. There were 3 deaths (0.059%) from pulmonary embolism (PE). Of 123 VTEs identified, 55 had PE, 17 had above knee deep vein thrombosis (DVT), 28 had calf DVT and 14 had been incorrectly coded as VTE. There was considerable inappropriate treatment of calf DVT with resultant morbidity. There was an increase in diagnosis of PE between days 1 and 5 post surgery in the later part of the study, corresponding with increasing use of CT Pulmonary Angiography. Increasing diagnosis of PE may be due to detection of embolic debris from surgery due to greater vigilance rather than post-operative thromboembolism. Death from PE is rare following TKR. |
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Authors:
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Robert A E Clayton; Paul Gaston; Adam C Watts; Colin R Howie |
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Publication Detail:
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Type: Journal Article Date: 2008-11-12 |
Journal Detail:
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Title: The Knee Volume: 16 ISSN: 0968-0160 ISO Abbreviation: Knee Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2008-12-26 Completed Date: 2009-03-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9430798 Medline TA: Knee Country: England |
Other Details:
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Languages: eng Pagination: 18-21 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery, Royal Infirmary of Edinburgh, Little France Crescent, Edinburgh EH16 4SU, United Kingdom. RAEClayton@onetel.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arthroplasty, Replacement, Knee
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adverse effects*,
statistics & numerical data Humans Incidence Pulmonary Embolism / epidemiology*, etiology Registries* Scotland / epidemiology Venous Thromboembolism / epidemiology*, etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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