| Thromboembolic complications in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. | |
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MedLine Citation:
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PMID: 16760233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Incidence and clinical presentation of thromboembolic complications in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) were analysed. In reports on ARVD/C, thromboembolism is rarely mentioned. The possible risk factors are: right ventricle (RV) dilatation, aneurysms, and wall motion abnormalities. METHODS AND RESULTS: A group of 126 patients (89 male, 37 female, aged 43.6+/-14.3) with ARVD/C was retrospectively analysed for the presence of thromboembolic complications. The mean follow-up period was 99+/-64 months. Thromboembolic complications, i.e. pulmonary embolism (n=2), RV outflow tract thrombosis with severe RV failure (n=1), and cerebrovascular accident associated with atrial fibrillation (n=2) were observed in 4% of the patients. Spontaneous echogenic contrast was observed in seven patients with severe damage to RV. In four of them supraventricular arrhythmias resulting in heart failure were reported. Annual incidence of thromboembolic complications was 0.5/100 patients. CONCLUSIONS: (i) ARVD/C may be complicated by thrombosis. Annual incidence of such complications is significantly lower than reported for left ventricle failure. (ii) Anticoagulation should be used in ARVD/C patients with large, hypokinetic RV and slow blood flow. (iii) Patients with severe forms of ARVD/C, thrombus formation in the RV and/or spontaneous echocardiographic contrast are at higher risk of a poor outcome. |
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Authors:
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Elzbieta Katarzyna Wlodarska; Olgierd Wozniak; Marek Konka; Wanda Rydlewska-Sadowska; Andrzej Biederman; Piotr Hoffman |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2006-06-07 |
Journal Detail:
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Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 8 ISSN: 1099-5129 ISO Abbreviation: Europace Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-07-25 Completed Date: 2006-12-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
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Languages: eng Pagination: 596-600 Citation Subset: IM |
Affiliation:
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Department of Congenital Heart Diseases, Department of Cardiosurgery, Institute of Cardiology, Alpejska 42, 04-628 Warsaw, Poland. wlodarsk@ikard.waw.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticoagulants / therapeutic use Arrhythmogenic Right Ventricular Dysplasia / complications*, pathology, physiopathology* Dilatation, Pathologic / pathology Echocardiography Female Heart Ventricles / pathology, physiopathology Humans Incidence Male Middle Aged Prognosis Regional Blood Flow / physiology Retrospective Studies Risk Factors Thromboembolism / etiology*, pathology, physiopathology*, prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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