Document Detail

Thromboelastometry guided therapy of severe bleeding. Essener Runde algorithm.
MedLine Citation:
PMID:  23258612     Owner:  NLM     Status:  Publisher    
Both, severe haemorrhage and blood transfusion are associated with increased morbidity and mortality. Therefore, it is of particular importance to stop perioperative bleeding as fast and as possible to avoid unnecessary transfusion. Viscoelastic test (ROTEM® or TEG®) allow for early prediction of massive transfusion and goal-directed therapy with specific haemostatic drugs, coagulation factor concentrates, and blood products. Growing consensus points out, that plasma-based coagulation screening tests like aPTT and PT are inappropriate for monitoring coagulopathy or guide transfusion therapy. Increasing evidence of more than 5000 surgical / trauma patients points towards the beneficial effects of a thrombelastography or -metry based approach in diagnosis and goal-directed therapy of perioperative massive haemorrhage. The Essener Runde task force is a group of clinicians of various specialties (anaesthesiology, intensive care, haemostaseology, haematology, internal medicine, transfusion medicine, surgery) interested in perioperative coagulation management. The ROTEM diagnostic algorithm of the Essener Runde task force was created to standardise and simplify the interpretation of ROTEM® results in perioperative settings and to present their possible implications for therapeutic interventions in severe bleeding. To exemplify, this text mainly focuses on coagulation management in trauma.
H Lier; M Vorweg; A Hanke; K Görlinger
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-20
Journal Detail:
Title:  Hamostaseologie     Volume:  33     ISSN:  0720-9355     ISO Abbreviation:  Hamostaseologie     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8204531     Medline TA:  Hamostaseologie     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Dr. Heiko Lier, Department of Anaesthesiology and Intensive Care, Medicine University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany, Tel. +49/(0)221/47 80, Pager: 1097, Fax +49/(0)221/478 60 93, E-mail:,
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