Document Detail

Thrombocytopenic purpura and anemia in a breast-fed infant whose mother was treated with valproic acid.
MedLine Citation:
PMID:  9202628     Owner:  NLM     Status:  MEDLINE    
Valproic acid is an antiepileptic drug in widespread use. The possibility of various hematologic side effects with this drug is well recognized. We describe a breast-fed infant with thrombocytopenic purpura, anemia, and reticulocytosis, whose mother was treated with valproic acid. As the mother stopped breast-feeding, the infant recovered.
M M Stahl; J Neiderud; E Vinge
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  130     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-07-17     Completed Date:  1997-07-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1001-3     Citation Subset:  AIM; IM    
Pharmacoepidemiology Unit, Medical Products Agency, Uppsala, Sweden.
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MeSH Terms
Anemia / etiology*
Anticonvulsants / adverse effects*,  therapeutic use
Breast Feeding*
Epilepsy / drug therapy
Infant, Newborn
Maternal Welfare*
Purpura, Thrombocytopenic / etiology*
Valproic Acid / adverse effects*,  therapeutic use
Reg. No./Substance:
0/Anticonvulsants; 99-66-1/Valproic Acid

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