| Thrombocytopenia in preeclampsia and eclampsia. | |
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MedLine Citation:
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PMID: 6813969 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. The lack of a general agreement on the definition of PE makes the interpretation of laboratory findings in different series of these patients difficult. 2. Thrombocytopenia is the most common hemostatic abnormality in patients with PE and is caused by platelet consumption. 3. There is little concrete evidence that thrombin mediates the thrombocytopenia in most of these patients. 4. Immune mechanisms or severe vasospasm with resultant endothelial damage may contribute to the thrombocytopenia in some patients. |
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Authors:
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B Gibson; D Hunter; P B Neame; J G Kelton |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Seminars in thrombosis and hemostasis Volume: 8 ISSN: 0094-6176 ISO Abbreviation: Semin. Thromb. Hemost. Publication Date: 1982 Jul |
Date Detail:
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Created Date: 1982-12-16 Completed Date: 1982-12-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0431155 Medline TA: Semin Thromb Hemost Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 234-47 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic
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blood,
complications Disseminated Intravascular Coagulation / blood, complications Eclampsia / blood* Epoprostenol / biosynthesis Factor VIII / biosynthesis Female Fibrin / metabolism Fibrin Fibrinogen Degradation Products / analysis Fibrinogen / analysis Fibrinopeptide A / biosynthesis Humans Hypertension / complications Platelet Count Pre-Eclampsia / blood*, complications, pathology Pregnancy Pregnancy Complications, Hematologic / blood* Thrombin / metabolism Thrombocytopenia / blood*, complications Thromboxane A2 / biosynthesis |
| Chemical | |
Reg. No./Substance:
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0/Fibrin Fibrinogen Degradation Products; 0/fibrinmonomer; 25422-31-5/Fibrinopeptide A; 35121-78-9/Epoprostenol; 57576-52-0/Thromboxane A2; 9001-27-8/Factor VIII; 9001-31-4/Fibrin; 9001-32-5/Fibrinogen; EC 3.4.21.5/Thrombin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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