Document Detail

Thrombocytopenia in patients receiving oral anticoagulant therapy.
MedLine Citation:
PMID:  12361197     Owner:  NLM     Status:  MEDLINE    
The aim of this report was to determine the frequency of thrombocytopenia in a cohort of 1,126 patients receiving oral anticoagulant therapy (OAT), and to compare the grade of thrombocytopenia and the severity of bleeding complications. Severe thrombocytopenia was observed in five patients, and moderate and light thrombocytopenia were observed in 208 patients. Thrombocytopenic patients receiving OAT presented five major and six minor hemorrhages. The presence of hepatitis markers and autoantibodies was assessed. All parameters at the time of the bleeding complication were in the therapeutic range.
Gianluca Sottilotta; Vincenzo Oriana; Caterina Latella; Vincenzo Trapani Lombardo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis     Volume:  8     ISSN:  1076-0296     ISO Abbreviation:  Clin. Appl. Thromb. Hemost.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-10-03     Completed Date:  2003-07-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9508125     Medline TA:  Clin Appl Thromb Hemost     Country:  United States    
Other Details:
Languages:  eng     Pagination:  213-5     Citation Subset:  IM    
Centro Emofilia Servizio Emostasi Trombosi, Azienda Ospedaliera Bianchi-Melacrino-Morelli, Reggio Calabria, Italy.
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MeSH Terms
Administration, Oral
Aged, 80 and over
Anticoagulants / adverse effects*,  therapeutic use
Autoantibodies / blood
Cohort Studies
Hemorrhage / chemically induced
Hepatitis B / etiology
Hepatitis C / etiology
Middle Aged
Postoperative Complications
Thrombocytopenia / chemically induced*
Reg. No./Substance:
0/Anticoagulants; 0/Autoantibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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