Document Detail

Thrombelastographic patterns following abdominal aortic surgery.
MedLine Citation:
PMID:  7818056     Owner:  NLM     Status:  MEDLINE    
Postoperative changes in thrombelastographic patterns were studied in thirty patients undergoing elective abdominal aortic bypass surgery. Native whole blood thrombelastography was performed preoperatively and on days 1, 2, and 3 postoperatively. The thrombelastographic changes included a decrease in r on day one (P < 0.0001), with concurrent increases in alpha (P < 0.0001) and MA (P < 0.001). On days 2 and 3 there were further increases in MA (P < 0.0001). These changes indicate enhanced procoagulant activity and progressive increases in maximum clot strength. The results confirm that hypercoagulability occurs in whole blood following abdominal aortic bypass surgery. Further studies are warranted to determine whether modification of postoperative hypercoagulability reduces the incidence of thrombotic complications in this group of patients.
N M Gibbs; G P Crawford; N Michalopoulos
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  22     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-02-09     Completed Date:  1995-02-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  534-8     Citation Subset:  IM    
Department of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
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MeSH Terms
Aged, 80 and over
Analgesia, Epidural
Anesthesia, General
Antithrombin III / analysis
Aorta, Abdominal / surgery*
Aspirin / therapeutic use
Blood Coagulation / physiology*
Blood Loss, Surgical
Blood Transfusion
Factor VIII / analysis
Fibrinogen / analysis
Fluid Therapy
Middle Aged
Platelet Count
Thrombosis / prevention & control
Reg. No./Substance:
50-78-2/Aspirin; 9000-94-6/Antithrombin III; 9001-27-8/Factor VIII; 9001-32-5/Fibrinogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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