Document Detail


Three's company: the fission yeast actin cytoskeleton.
MedLine Citation:
PMID:  21145239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
How the actin cytoskeleton assembles into different structures to drive diverse cellular processes is a fundamental cell biological question. In addition to orchestrating the appropriate combination of regulators and actin-binding proteins, different actin-based structures must insulate themselves from one another to maintain specificity within a crowded cytoplasm. Actin specification is particularly challenging in complex eukaryotes where a multitude of protein isoforms and actin structures operate within the same cell. Fission yeast Schizosaccharomyces pombe possesses a single actin isoform that functions in three distinct structures throughout the cell cycle. In this review we explore recent studies in fission yeast that help unravel how different actin structures operate in cells.
Authors:
David R Kovar; Vladimir Sirotkin; Matthew Lord
Related Documents :
15365179 - Par-1 promotes a hepatic mode of apical protein trafficking in mdck cells.
2714099 - Differential synthesis and phosphorylation of the alpha-crystallin a and b chains durin...
12647809 - Leukotriene synthesis by epithelial cells.
3720669 - Estrogen stimulation of deoxyribonucleic acid synthesis in uterine epithelial cells whi...
6189269 - Demonstration of keratin filaments in thymic nurse cells (tnc) and alloreactivity of tn...
12567739 - The preliminary experimental study of induced differentiation of embryonic stem cells i...
15558029 - Cytoskeletal modification of rho guanine nucleotide exchange factor activity: identific...
21370169 - Preparation and use of thermosensitive polymers.
9096339 - Cell cycle independent interaction of cdc2 with the centrosome, which is associated wit...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2010-12-07
Journal Detail:
Title:  Trends in cell biology     Volume:  21     ISSN:  1879-3088     ISO Abbreviation:  Trends Cell Biol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-07     Completed Date:  2011-04-25     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  9200566     Medline TA:  Trends Cell Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  177-87     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA. drkovar@uchicago.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Actins / metabolism*
Animals
Cell Cycle
Cytoskeleton / metabolism*
Endocytosis
Humans
Protein Binding
Schizosaccharomyces / cytology,  metabolism*
Grant Support
ID/Acronym/Agency:
R01 GM079265/GM/NIGMS NIH HHS; R01 GM079265-05/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Actins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Inhibition of ?-carbonic anhydrases with ureido-substituted benzenesulfonamides.
Next Document:  The impact of tilting on blood flow and localized tissue loading.