Document Detail

Three-year changes in fitness and adiposity are independently associated with cardiovascular risk factors among young Danish children.
MedLine Citation:
PMID:  20231753     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: It is not clear the extent to which change in adiposity and cardiovascular fitness (CRF) during early childhood are associated with change in cardiovascular risk factors or if associations are independent or interactive. METHODS: 383 Danish children were examined at ages 6 and 9. CRF, sum of skinfolds (SSF), and blood pressure were assessed. Fasting blood samples were used to calculate total cholesterol (TC), high and low density lipoprotein cholesterol (HDL-C & LDL-C), triglycerides, insulin, glucose, and HOMA-IR. Regression models examined whether CRF change or SSF change were independently or interactively associated with risk variables. RESULTS: Change in SSF was independently associated with change in TC (z = 4.83, P < .001), LDL-C (z = 4.38, P < .001), systolic (z = 3.45, P < .001), and diastolic (z = 2.45, P = .014) blood pressure. CRF change was independently associated with change in TC (z = -3.86, P < .001), HDL-C (z = 3.85, P < .001), and systolic blood pressure (z = 2.06, P = .040). CONCLUSIONS: Change in fitness and adiposity were independently associated with the development of cardiovascular risk factors among young children suggesting a need to increase CRF and prevent weight gain early during development to improve cardiovascular health.
Russell Jago; Karsten Froberg; Ashley R Cooper; Stig Eiberg; Lars Bo Andersen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of physical activity & health     Volume:  7     ISSN:  1543-3080     ISO Abbreviation:  J Phys Act Health     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-03-16     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101189457     Medline TA:  J Phys Act Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  37-44     Citation Subset:  IM    
Department of Exercise, Nutrition, and Health Sciences, University of Bristol, Bristol, UK.
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MeSH Terms
Age Factors
Analysis of Variance
Cardiovascular Diseases / epidemiology*,  etiology
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Denmark / epidemiology
Exercise Test
Lipids / blood*
Models, Statistical
Multivariate Analysis
Physical Fitness*
Regression Analysis
Risk Factors
Statistics as Topic
Time Factors
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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