Document Detail


Three new triterpenoids from Panax ginseng exhibit cytotoxicity against human A549 and Hep-3B cell lines.
MedLine Citation:
PMID:  22529048     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Three new triterpenoid derivatives, 3-O-β-D: -glucopyranosyl-20(S)-protopanaxtriol (1), 3-formyloxy-20-O-β-D: -glucopyranosyl-20(S)-protopanaxtriol (2) and 26-hydroxyl-24(E)-20(S)-protopanaxtriol (3), along with six known ginsenosides, were isolated from leaves of Panax ginseng. Their structures were established on the basis of spectral analysis (IR, 1D and 2D NMR, HRESI-MS). Compounds 1-3 exhibited various degree of cytotoxicity towards human A549 pulmonary carcinoma cells and Hep3B hepatoma cells.
Authors:
Hai-Ying Ma; Hui-Yuan Gao; Jian Huang; Bo-Hang Sun; Bo Yang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-12
Journal Detail:
Title:  Journal of natural medicines     Volume:  -     ISSN:  1861-0293     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101518405     Medline TA:  J Nat Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Pharmacy Department, The Fourth Affiliated Hospital of China Medical University, No. 4, Chongshan Eastern Road, Yuhong District, Shenyang, 110032, China, cmu4h-mhy@126.com.
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