Document Detail


Three new C21-steroidal glycosides from the roots of Cynanchum inamoenum.
MedLine Citation:
PMID:  17994395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three new C(21)-steroidal glycosides presenting an unusual 13,14:14,15-disecopregnane-type skeleton, named inamosides A-C (1-3), together with two known C(21)-steroidal glycosides, were isolated from the MeOH extract of the roots of Cynanchum inamoeum (Maxim.) Loes (Asclepiadaceae). The aglycone of compounds 1, 2, and 3 has a 2beta-hydroxyl, which has not yet been reported in the literature. The structure and relative configuration of the aglycone of compounds 1, 2, and 3 were established by X-ray crystallographic analysis.
Authors:
Li-Qin Wang; Yang Lu; You-Xing Zhao; Jun Zhou; Qi-Tai Zheng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of Asian natural products research     Volume:  9     ISSN:  1028-6020     ISO Abbreviation:  J Asian Nat Prod Res     Publication Date:    2007 Sep-Dec
Date Detail:
Created Date:  2007-11-12     Completed Date:  2008-05-14     Revised Date:  2009-07-21    
Medline Journal Info:
Nlm Unique ID:  100888334     Medline TA:  J Asian Nat Prod Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  771-9     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Kunming, China.
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MeSH Terms
Descriptor/Qualifier:
Asclepiadaceae / chemistry*
Crystallography, X-Ray
Glycosides / chemistry,  isolation & purification*
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Roots / chemistry*
Steroids / chemistry,  isolation & purification*
Chemical
Reg. No./Substance:
0/Glycosides; 0/Steroids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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