Document Detail

Three-month prevalence rates of gastrointestinal symptoms and the influence of demographic factors: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST).
MedLine Citation:
PMID:  10565620     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This paper reports the 3-month prevalence rates of gastrointestinal (GI) symptoms from the Domestic/International Gastroenterology Surveillance Study (DIGEST), and their relationship with demographic factors; namely age, gender and body mass index (BMI). METHODS: Subjects were recruited from 10 international sites by a total of 5581 face-to-face interviews conducted with randomly selected members of the general population aged 18 years and over (50.6% female; mean age 44 years). The sample was divided according to whether subjects reported 1 or more of 14 GI symptoms, or no GI symptoms. Those with any of 11 upper GI symptoms were then subdivided according to their most bothersome symptom: gastro-oesophageal reflux (GORD)-like symptoms, ulcer-like symptoms or dysmotility-like symptoms. Symptoms were classified as relevant if they were of at least moderate severity and/or occurred at least once a week. RESULTS: A mean of 46.4% of subjects reported experiencing one or more of the 14 GI symptoms, with 28.1% experiencing upper GI symptoms classified as relevant. Significant differences between the prevalences of relevant symptoms were evident between sampling sites. The estimated prevalence of GORD-like symptoms for the pooled sample was 7.7%. For ulcer-like symptoms, prevalence was 4.1%, and for dysmotility-like symptoms 15.5%. Significant differences were observed in the prevalence rates of symptom groups between countries. Women were significantly more likely than men to experience relevant symptoms, with gender differences also observed in the rates of GORD-like and dysmotility-like symptoms. The proportion of those with relevant symptoms experiencing GORD-like symptoms increased significantly with age; ulcer-like symptoms showed no significant relationship with age; and dysmotility-like symptoms decreased significantly with age. The prevalence of relevant symptoms increased with increasing BMI. CONCLUSIONS: In conclusion, the DIGEST has provided valuable data on the cross-country prevalence of upper GI symptoms, and their association with biological factors.
V Stanghellini
Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology. Supplement     Volume:  231     ISSN:  0085-5928     ISO Abbreviation:  Scand. J. Gastroenterol. Suppl.     Publication Date:  1999  
Date Detail:
Created Date:  1999-12-07     Completed Date:  1999-12-07     Revised Date:  2008-02-13    
Medline Journal Info:
Nlm Unique ID:  0437034     Medline TA:  Scand J Gastroenterol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  20-8     Citation Subset:  IM    
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy.
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MeSH Terms
Body Mass Index
Canada / epidemiology
Cross-Sectional Studies
Dyspepsia / classification,  epidemiology
Finland / epidemiology
Gastrointestinal Diseases / classification*,  epidemiology*
Italy / epidemiology
Japan / epidemiology
Logistic Models
Middle Aged
Netherlands / epidemiology
Population Surveillance*
Quality of Life
Sampling Studies
Scandinavia / epidemiology
Switzerland / epidemiology
United States / epidemiology
Urban Population
World Health*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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