Document Detail


Three instructive cases of tiger snake (Notechis scutatus) envenomation--and how a radioimmunoassay proved the diagnosis.
MedLine Citation:
PMID:  904526     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three unusual cases are described, in which, in separate incidents, young snake bite victims were found comatose. Tiger snake vemon was detected by radioimmunoassay in the urine and serum, and in one case on the clothing of these children. Gross myoglobinuria was present in all cases. The three cases demonstrate clearly the myolytic potential of tiger snake venom if specific treatment (administration of antivenom) is delayed. Extreme elevation of serum enzyme levels was found in the two victims who survived. Evidence was obtained that the major neurotoxin of tiger snake venom is absorbed at least partly via the lymphatics and that some is excreted in the urine.
Authors:
S K Sutherland; A R Coulter
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  2     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-11-25     Completed Date:  1977-11-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  177-80     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aspartate Aminotransferases / blood
Child
Female
Humans
Kidney Failure, Acute / etiology
L-Lactate Dehydrogenase / blood
Male
Myoglobinuria / etiology
Radioimmunoassay
Snake Bites / complications,  diagnosis*,  enzymology
Snake Venoms / analysis*
Chemical
Reg. No./Substance:
0/Snake Venoms; EC 1.1.1.27/L-Lactate Dehydrogenase; EC 2.6.1.1/Aspartate Aminotransferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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