Document Detail

Three-dimensional time-of-flight (3D TOF) magnetic resonance angiography (MRA) and contrast-enhanced MRA of intracranial aneurysms treated with platinum coils.
MedLine Citation:
PMID:  18300146     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Contrast-enhanced magnetic resonance angiography (CE-MRA) is less prone to flow-related signal intensity loss than three-dimensional time-of-flight (3D TOF) MRA and may therefore be more sensitive for detection of residual patency in platinum coil-treated intracranial aneurysms.
PURPOSE: To compare MRA and CE-MRA in the follow-up of intracranial aneurysms treated with platinum coils.
MATERIAL AND METHODS: CE-MRA and 3D TOF MRA (pre- and postcontrast injection) of the intracranial vasculature was performed at 1.5T in 38 patients (47 aneurysms) referred for DSA in the follow-up of coiled intracranial aneurysms.
RESULTS: DSA showed aneurysm patency in 22/47 investigations. Patent aneurysm components were observed with CE-MRA in 18/22 cases, and with 3D TOF MRA in 21/22 cases. There was no significant difference in patent aneurysm component size between CE-MRA and 3D TOF MRA. In addition, CE-MRA showed six, 3D TOF MRA before contrast injection showed seven, and 3D TOF MRA after contrast injection showed eight cases with patent aneurysm components not observed on DSA.
CONCLUSION: 3D TOF MRA was highly sensitive for detection of patent aneurysm components, and at least as sensitive as CE-MRA. Residual aneurysm patency seems to be better visualized with MRA than with DSA in some cases.
J Wikström; E Ronne-Engström; G Gal; P Enblad; M Tovi
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Acta radiologica (Stockholm, Sweden : 1987)     Volume:  49     ISSN:  1600-0455     ISO Abbreviation:  Acta Radiol     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-26     Completed Date:  2008-03-27     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  8706123     Medline TA:  Acta Radiol     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  190-6     Citation Subset:  IM    
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MeSH Terms
Angiography, Digital Subtraction / methods
Carotid Artery, Internal / radiography
Contrast Media / administration & dosage
Embolization, Therapeutic / methods*
Follow-Up Studies
Gadolinium DTPA / diagnostic use
Image Enhancement / methods
Image Processing, Computer-Assisted / methods
Imaging, Three-Dimensional / methods*
Intracranial Aneurysm / diagnosis*,  therapy*
Magnetic Resonance Angiography / methods*
Platinum / therapeutic use*
Predictive Value of Tests
Prospective Studies
Reference Standards
Reproducibility of Results
Sensitivity and Specificity
Treatment Outcome
Vascular Patency
Vertebral Artery / radiography
Reg. No./Substance:
0/Contrast Media; 122795-43-1/gadodiamide; 49DFR088MY/Platinum; K2I13DR72L/Gadolinium DTPA
Erratum In:
Acta Radiol. 2009 Apr;50(3):349

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