Document Detail

Three-dimensional placental volume measurements between 11 and 13 weeks' gestation.
MedLine Citation:
PMID:  18979413     Owner:  NLM     Status:  MEDLINE    
We sought to determine whether three-dimensional (3D) placental volume measurements can be assessed in normal pregnancies between 11 and 13 weeks' gestation with good intraobserver accuracy. Twenty normal pregnancies were included. Placental volume was determined twice, using the virtual organ computer-aided analysis method. Three-dimensional placental volume measurements were performed by a single physician. Patients with multiple pregnancies, first-trimester bleeding, and abnormal placental appearance were excluded. Intraobserver reliability was evaluated by kappa analysis, and Student T test was performed for continuous variables. Mean placental volume (MPV) was 67.5 +/- 26.7 mL (3) between 11 and 13 weeks' gestation. No significant differences were noted between the two examinations performed (MPV of 67.5 +/- 26.7 mL (3) during the first versus 65.6 +/- 29.1 mL (3) during the second examination; p = 0.826). Moreover, the intraobserver agreement was excellent as indicated by kappa of 0.8. Placental volume can be assessed by 3D sonography between 11 and 13 weeks' gestation with minimal deviations. Nevertheless, the broad variability in placental volume with a wide standard deviation makes its clinical significance questionable.
Eliezer Burstein; Eyal Sheiner; Reli Hershkovitz
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Publication Detail:
Type:  Journal Article     Date:  2008-10-31
Journal Detail:
Title:  American journal of perinatology     Volume:  26     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-06-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-71     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Beer-Sheva, Israel.
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MeSH Terms
Gestational Age
Image Processing, Computer-Assisted
Organ Size
Placenta / anatomy & histology*,  ultrasonography*
Prospective Studies
Reproducibility of Results
Ultrasonography, Prenatal*

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