Document Detail

Three-dimensional microtomographic imaging of human brain cortex.
MedLine Citation:
PMID:  18289513     Owner:  NLM     Status:  MEDLINE    
This paper describes an X-ray microtomographic technique for imaging the three-dimensional structure of the human cerebral cortex. Neurons in the brain constitute a neural circuit as a three-dimensional network. The brain tissue is composed of light elements that give little contrast in a hard X-ray transmission image. The contrast was enhanced by staining neural cells with metal compounds. The obtained structure revealed the microarchitecture of the gray and white matter regions of the frontal cortex, which is responsible for the higher brain functions.
Ryuta Mizutani; Akihisa Takeuchi; Kentaro Uesugi; Masami Ohyama; Susumu Takekoshi; R Yoshiyuki Osamura; Yoshio Suzuki
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Publication Detail:
Type:  Journal Article     Date:  2008-01-26
Journal Detail:
Title:  Brain research     Volume:  1199     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-10     Completed Date:  2008-09-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  53-61     Citation Subset:  IM    
Department of Applied Biochemistry, School of Engineering, Tokai University, Kitakaname 1117, Hiratsuka, Kanagawa 259-1292, Japan.
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MeSH Terms
Brain Mapping
Cerebral Cortex / anatomy & histology*
Imaging, Three-Dimensional / methods*
Tomography, X-Ray Computed / methods*

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