Document Detail

Three-dimensional inversion rendering in the first- and early second-trimester fetal brain: its use in holoprosencephaly.
MedLine Citation:
PMID:  18956427     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To explore the feasibility and added value of three-dimensional (3D) inversion rendering of the developing embryonic/fetal ventricular system, and to apply this display technique to enhance the sonographic examination of holoprosencephaly. METHODS: 3D volumes of the embryonic/fetal brain were acquired from four normal fetuses at 8-11 postmenstrual weeks, and four fetuses diagnosed with holoprosencephaly between 9 and 14 postmenstrual weeks. The volumes were then analyzed offline to obtain inversion rendered 3D shapes of the ventricular systems. RESULTS: All inversion rendering displays were successful and provided the opportunity to study normal as well as pathological aspects of the early fetal brain. CONCLUSIONS: Inversion rendering of early fetal brain ventricles is feasible and should be attempted if additional information about the early normal or pathological fetal brain is needed. It may have scientific value in embryologic or genetic studies.
I E Timor-Tritsch; A Monteagudo; R Santos
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Publication Detail:
Type:  Case Reports; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  32     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-03     Completed Date:  2009-06-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  744-50     Citation Subset:  IM    
Copyright Information:
(c) 2008 ISUOG. Published by John Wiley & Sons, Ltd.
Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY 10016, USA.
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MeSH Terms
Brain / embryology,  ultrastructure*
Cerebral Ventricles / ultrasonography
Diseases in Twins / embryology,  ultrasonography
Feasibility Studies
Fetal Development
Holoprosencephaly / ultrasonography*
Imaging, Three-Dimensional / methods*
Pregnancy Trimester, First
Pregnancy Trimester, Second
Ultrasonography, Prenatal / methods*

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