Document Detail

Three-dimensional electroanatomic mapping of the coronary veins during cardiac resynchronization therapy implant: feasibility and possible applications.
MedLine Citation:
PMID:  25005455     Owner:  NLM     Status:  Publisher    
PURPOSE: Left ventricular (LV) electrical activation pattern could determine optimal LV lead placement site during cardiac resynchronization therapy (CRT) device implant. We sought to determine the feasibility of using EnSite NavX™ electroanatomic mapping system (St. Jude Medical Inc., St. Paul, MN) to assess LV electrical activation during CRT implant.
METHODS: Patients (n = 32; NYHA III, LVEF <35 %, QRSd >120 ms) underwent NavX™ mapping during CRT implant. Left bundle branch block (LBBB) was present during sinus rhythm in group A (n = 17), whereas LBBB was induced by permanent RV apical pacing in group B (n = 15). Following coronary sinus (CS) cannulation, a coil tip 0.014-in. guidewire was introduced into all available CS branches as a mapping electrode. Each patient's unipolar activation map was successfully constructed within 10 min, using the onset of surface QRS as reference.
RESULTS: LV activation patterns were complex and varied in both groups. Earliest activation was usually apical, but latest activation was more heterogenous. The lateral or posterolateral branches were the sites of latest activation in 47 % of group A and 73 % of group B. An LV lead positioned conventionally by a physician blinded to the mapping data was concordant with the latest activated segment in 18 % of group A and none of group B patients.
CONCLUSIONS: Electroanatomic mapping of the CS tributaries is feasible and clinically practicable. Mapping revealed heterogenous conduction patterns that vary between patients in each group and between groups. An LV lead empirically placed in a lateral branch rarely paces the optimal, latest activated vein segment.
Imran Niazi; Kyungmoo Ryu; Richard Hood; Indrajit Choudhuri; Masood Akhtar
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-7-9
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  -     ISSN:  1572-8595     ISO Abbreviation:  J Interv Card Electrophysiol     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-7-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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