Document Detail

Three-dimensional delayed gadolinium-enhanced magnetic resonance imaging of hip joint cartilage at 3T: A prospective controlled study.
MedLine Citation:
PMID:  22591759     Owner:  NLM     Status:  Publisher    
PURPOSE: To assess acetabular and femoral hip joint cartilage with three-dimensional (3D) delayed gadolinium-enhanced magnetic resonance imaging (dGEMRIC) in patients with degeneration of hip joint cartilage and asymptomatic controls with morphologically normal appearing cartilage. METHODS AND MATERIALS: A total of 40 symptomatic patients (18 males, 22 females; mean age: 32.8±10.2 years, range: 18-57 years) with different hip joint deformities including femoroacetabular impingement (n=35), residual hip dysplasia (n=3) and coxa magna due to Legg-Calve-Perthes disease in childhood (n=2) underwent high-resolution 3D dGEMRIC for the evaluation of acetabular and femoral hip joint cartilage. Thirty-one asymptomatic healthy volunteers (12 males, 19 females; mean age: 24.5±1.8 years, range: 21-29 years) without underlying hip deformities were included as control. MRI was performed at 3T using a body matrix phased array coil. Region of interest (ROI) analyses for T1(Gd) assessment was performed in seven regions in the hip joint, including anterior to superior and posterior regions. RESULTS: T1(Gd) mapping demonstrated the typical pattern of acetabular cartilage consistent with a higher glycosaminoglycan (GAG) content in the main weight-bearing area. T1(Gd) values were significantly higher in the control group than in the patient group whereas significant differences in T1(Gd) values corresponding to the amount of cartilage damage were noted both in the patient group and in the control group. CONCLUSIONS: Our study demonstrates the potential of high-resolution 3D dGEMRIC at 3T for separate acetabular and femoral hip joint cartilage assessment in various forms of hip joint deformities.
Christoph Zilkens; Falk Miese; Young-Jo Kim; Harish Hosalkar; Gerald Antoch; Rüdiger Krauspe; Bernd Bittersohl
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-14
Journal Detail:
Title:  European journal of radiology     Volume:  -     ISSN:  1872-7727     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Univ. Dusseldorf, Medical Faculty, Department of Orthopaedic Surgery, Moorenstraße 5, D-40225 Dusseldorf, Germany.
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