| Three-dimensional high-speed optical coherence tomography for diagnosis of hypotony maculopathy after glaucoma filtration surgery. | |
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MedLine Citation:
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PMID: 19855288 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To describe the clinical findings of hypotony maculopathy using 3-dimensional (3D) topography maps reconstructed from spectral domain optical coherence tomography (SD-OCT) imaging, and compare SD-OCT with time domain OCT (TD-OCT) for hypotony maculopathy diagnosis. METHODS: This was an observational noncomparative case series comprising 7 patients with hypotony maculopathy after trabeculectomy with mitomycin-C. All patients underwent consecutive imaging with TD-OCT (Stratus OCT) and SD-OCT using various high-resolution instruments. 3-D surface maps obtained using SD-OCT were compared with linear scans obtained using TD-OCT. RESULTS: Two of 7 eyes had minimally detectable folds with TD-OCT imaging in the vertical axis. Five eyes did not show folds on TD-OCT. 3-D topographic maps using SD-OCT demonstrated advanced retinal and subretinal folds throughout the macular region in all 7 patients. All eyes (4 cases) with no topographically detectable folds using SD-OCT within the foveal avascular zone had visual acuity of 20/25 or better. Three eyes with obvious contour disruption within the foveal pit had visual acuity ranging from 20/30 to 20/70. CONCLUSIONS: SD-OCT using 3-D surface topography mapping provides greater sensitivity for hypotony maculopathy diagnosis and monitoring as compared with TD-OCT. Disruption of the foveal pit as detected using SD-OCT is associated with reduced visual acuity. |
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Authors:
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Margot L Goodkin; Dilraj S Grewal; David S Greenfield |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of glaucoma Volume: 19 ISSN: 1536-481X ISO Abbreviation: J. Glaucoma Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-16 Completed Date: 2010-10-08 Revised Date: 2011-08-03 |
Medline Journal Info:
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Nlm Unique ID: 9300903 Medline TA: J Glaucoma Country: United States |
Other Details:
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Languages: eng Pagination: 349-55 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Palm Beach Gardens, FL 33418, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Alkylating Agents / administration & dosage Female Glaucoma / surgery* Humans Imaging, Three-Dimensional Intraocular Pressure Macula Lutea / pathology* Male Middle Aged Mitomycin / administration & dosage Ocular Hypotension / diagnosis*, etiology Retinal Diseases / diagnosis*, etiology Risk Factors Tomography, Optical Coherence* Tonometry, Ocular Trabeculectomy / adverse effects* Visual Acuity |
| Grant Support | |
ID/Acronym/Agency:
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R01 EY013516-07/EY/NEI NIH HHS; R01-EY013516/EY/NEI NIH HHS; R01-EY08684/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Alkylating Agents; 50-07-7/Mitomycin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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