Document Detail


Three components of obstructive sleep apnea/hypopnea syndrome.
MedLine Citation:
PMID:  12667167     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aims of this study were to calculate the apnea-hypopnea index (AHI), which represented as the number of apnea-hypopnea occurrences per hour, the 4% oxygen desaturation index (ODI4) and the breathing-related arousal index (B-ArI) in polysomnographic studies of obstructive sleep apnea/hypopnea syndrome (OSAHS) patients and to investigate whether there was any relationship between each pair of scoring schemes. Thirty-four cases of OSAHS were studied. Total OSAHS patients were subdivided into those with a high AHI (> 25), and those with a low AHI (< 25). The correlation between each pair of scoring schemes for OSAHS with a high AHI showed high value. The correlation between AHI and ODI4 for OSAHS with a low AHI was 0.18 and that between AHI and B-ArI showed a weak correlation of 0.59, while that between ODI4 and B-ArI was only -0.078. Our results mean that oxygen desaturation and arousal occur separately in mild or moderate OSAHS patients, even though they are diagnosed with the same level of OSAHS by means of AHI. Breathing-related arousal without oxygen desaturation often occurs in mild or moderate OSAHS patients. We previously reported that AHI does not accurately reflect the severity of the increase in negativity of esophageal pressure manifested as respiratory efforts. We consider that the comprehension and assessment of OSAHS can be improved by the systematic differentiations among the three components: oxygen desaturation, arousals and respiratory efforts.
Authors:
Takayuki Kumano-go; Akira Mikami; Nakamori Suganuma; Hiroyoshi Adachi; Takuya Watanabe; Yoshihisa Shigedo; Yoshiro Sugita; Masatoshi Takeda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychiatry and clinical neurosciences     Volume:  57     ISSN:  1323-1316     ISO Abbreviation:  Psychiatry Clin. Neurosci.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-01     Completed Date:  2003-07-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9513551     Medline TA:  Psychiatry Clin Neurosci     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  197-203     Citation Subset:  IM    
Affiliation:
Osaka University Graduate School of Medicine, Course of Advanced Medicine, Department of Post-Genomics and Diseases, Division of Psychiatry and Behavioral Proteomics, Japan. kuma@psy.med.osaka-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Arousal / physiology
Female
Humans
Male
Middle Aged
Oxygen / blood
Polysomnography*
Predictive Value of Tests
Sleep Apnea Syndromes / diagnosis*,  psychology
Sleep Apnea, Obstructive / blood,  diagnosis*
Sleep Stages / physiology
Wakefulness / physiology
Work of Breathing / physiology
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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