Document Detail

Three cases of corticosteroid therapy triggering ventricular fibrillation in J-wave syndromes.
MedLine Citation:
PMID:  24281399     Owner:  NLM     Status:  Publisher    
We describe three cases of J-wave syndrome in which ventricular fibrillation (VF) was probably induced by corticosteroid therapy. The patients involved were being treated with prednisolone for concomitant bronchial asthma. One of the three patients had only one episode of VF during her long follow-up period (14 years). Two patients had hypokalemia during their VF episodes. Corticosteroids have been shown to induce various types of arrhythmia and to modify cardiac potassium channels. We discuss the possible association between corticosteroid therapy and VF in J-wave syndrome based on the cases we have encountered.
Naka Sakamoto; Nobuyuki Sato; Masahide Goto; Motoi Kobayashi; Naofumi Takehara; Toshiharu Takeuchi; Ahmed Karim Talib; Eitaro Sugiyama; Akiho Minoshima; Yasuko Tanabe; Kazumi Akasaka; Junichi Kawabe; Yuichiro Kawamura; Atsushi Doi; Naoyuki Hasebe
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-11-27
Journal Detail:
Title:  Heart and vessels     Volume:  -     ISSN:  1615-2573     ISO Abbreviation:  Heart Vessels     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-11-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511258     Medline TA:  Heart Vessels     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Cardiology, Asahikawa Medical University, Midorigaoka Higashi 2-1-1, Asahikawa, 078-8510, Japan.
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