Document Detail

Three-Dimensional Tracking of Carbon Nanotubes within Living Cells.
MedLine Citation:
PMID:  22624495     Owner:  NLM     Status:  Publisher    
Three-dimensional tracking of single walled carbon nanotubes (SWNT) with an orbital tracking microscope is demonstrated. We determine the viscosity regime (above 250 cP) at which the rotational diffusion coefficient can be used for length estimation. We also demonstrate SWNT tracking within live HeLa cells and use these findings to spatially map corral volumes (0.27-1.32 µm3), determine an active transport velocity (455 nm/s), and calculate local viscosities (54-179 cP) within the cell. With respect to the future use of SWNTs as sensors in living cells, we conclude that the sensor must change the fluorescence signal by at least 4-13% to allow separation of the sensor signal from fluctuations due to rotation of the SWNT when measuring with a time resolution of 32 ms.
Nigel Forest Reuel; Aurélie Dupont; Olivier Thouvenin; Don C Lamb; Michael S Strano
Related Documents :
19302825 - Aberrant intracellular igf-1r beta-subunit makes receptor knockout cells (igf1r-/-) sus...
208075 - Assay for early cytoplasmic effects of the src gene product of rous sarcoma virus.
2228315 - Immunochemical comparison of transformation-associated protein and secreted phosphoprot...
7251225 - Transformed and neoplastic phenotype: reversibility during culture by cell density and ...
22814725 - Development of flange and reticulate wall ingrowths in maize (zea mays l.) endosperm tr...
13677615 - Beta1-integrin and il-1alpha expression as bystander effect of medium from irradiated c...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-24
Journal Detail:
Title:  ACS nano     Volume:  -     ISSN:  1936-086X     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101313589     Medline TA:  ACS Nano     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Surveillance of adverse events following immunisation: the model of SAEFVIC, Victoria.
Next Document:  Hexanuclear Copper(II) Cages Built on a Central {?(3)-O···H···?(3)-O} Moiety, 1,3-Bis(dimethyl...