| Thoracoscopic lobectomy for stage I non-small cell lung cancer. | |
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MedLine Citation:
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PMID: 20813312 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Lobectomy via video-assisted thoracoscopic surgery (VATS) has a lower rate of morbidity and is less immunosuppressive than open lobectomy. Compared with open lobectomy, VATS lobectomy appears to have equivalent oncological results. We review the literature on perioperative outcomes, biological impact, and oncological results. Most published reports to date--although retrospective--suggest significant perioperative advantages to VATS lobectomy over open lobectomy. Data on acute phase reactants and cellular immunity show that VATS lobectomy causes less of an inflammatory response and is less immunosuppressive than open lobectomy. Mid- to long-term oncological results of patients with early-stage non-small cell lung cancer (NSCLC) appear to be equivalent for VATS and open lobectomy. Clinical evidence indicates that VATS lobectomy for early-stage NSCLC is associated with fewer postoperative complications and less negative biological impact than open lobectomy. Furthermore, all data to date strongly suggest oncological equivalence between VATS and open lobectomy for patients with early-stage NSCLC. |
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Authors:
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Rafael S Andrade; Michael A Maddaus |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Seminars in thoracic and cardiovascular surgery Volume: 22 ISSN: 1532-9488 ISO Abbreviation: Semin. Thorac. Cardiovasc. Surg. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-09-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8917640 Medline TA: Semin Thorac Cardiovasc Surg Country: United States |
Other Details:
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Languages: eng Pagination: 14-21 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of General Thoracic and Foregut Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA. andr0119@umn.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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