Document Detail


Thoracic manifestation of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-related disease. CT findings in 51 patients.
MedLine Citation:
PMID:  15480049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the pulmonary CT findings of patients with serum evidence of the myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA). METHODS: The pulmonary CT scans of 62 patients with serum evidence of MPO-ANCA (51 with microscopic polyangiitis, 11 with Churg-Strauss syndrome) were retrospectively assessed with regard to parenchymal, pleural, and mediastinal abnormalities. RESULTS: On the CT scans, abnormal findings were seen in 51 of the patients (82%, n = 62). Of the patients, the CT findings consisted of ground-glass attenuation in 48 of the patients (94%, n = 51), consolidation in 40 (78%), and thickening of bronchovascular bundles in 26 (51%). Pathologically, these findings corresponded to alveolar hemorrhages, interstitial chronic inflammation in the alveolar septa, vasculitis, or fibrosis. These abnormalities were predominantly seen in peripheral lung parenchyma (n = 37). CONCLUSION: The CT findings in patients with MPO-ANCA consisted mainly of ground-glass attenuation and consolidation in the peripheral lung. These findings, although nonspecific, are considered as pulmonary involvement in patients with MPO-ANCA.
Authors:
Yumiko Ando; Fumito Okada; Shunro Matsumoto; Hiromu Mori
Related Documents :
8451419 - Mycobacterium avium-intracellulare complex: evaluation with ct.
6624519 - Computed tomography in von hippel-lindau disease.
9576659 - Madelung disease: distribution of cervical fat and preoperative findings at sonography,...
22022639 - Value of acoustic radiation force impulse elastography for the assessment of ascites sy...
20931189 - Ct-guided corticosteroid injection for solitary eosinophilic granuloma of the spine.
3268159 - The natural history of subarachnoid haemorrhage with negative angiography: a prospectiv...
12434889 - Antigranulocyte monoclonal antibody immunoscintigraphy in inflammatory bowel disease in...
20976739 - Parkinson's disease and pathological gambling: results from a functional mri study.
25244349 - Validating biomarkers of treatable mechanisms in irritable bowel syndrome.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  28     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2004 Sep-Oct
Date Detail:
Created Date:  2004-10-14     Completed Date:  2006-07-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  710-6     Citation Subset:  IM    
Affiliation:
Department of Academic Radiology, Oita University Faculty of Medicine, Idaigaoka, Hasama-machi, Oita 879-5593, Japan. ANDOY@med.oita-u.ac.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Antibodies, Antineutrophil Cytoplasmic / blood*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Peroxidase / blood*
Retrospective Studies
Thoracic Diseases / blood*,  enzymology,  immunology,  radiography*
Tomography, X-Ray Computed*
Tumor Markers, Biological / blood*
Chemical
Reg. No./Substance:
0/Antibodies, Antineutrophil Cytoplasmic; 0/Tumor Markers, Biological; EC 1.11.1.7/Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  High incidence of chest malignancy detected by FDG PET in patients suspected of recurrent squamous c...
Next Document:  Biology of developmental and regenerative skeletogenesis.