Document Detail

Thoracic intramedullary sarcoidosis mimicking an intramedullary tumor.
MedLine Citation:
PMID:  18756925     Owner:  NLM     Status:  MEDLINE    
Sarcoidosis is a chronic, systemic granulomatous reticulosis of unknown origin, characterized by formation of hard tubercles and noncaseatinggranulomas. Since other infectious diseases such as berylliosis, mycobacterium and fungal infections may present with a noncaseating granulomas, histological diagnosis of sarcoidosis is made using the elimination method. Central nervous system manifestations of sarcoidosis may be present in 5-10% of the cases involving cranial nerves, leptomeninges and third ventricle respectively. Any part of the central nervous system can be affected. Involvement of spinal cord in sarcoidosis is extremely rare and presents with only 0.3-0.4% in patients with systemic sarcoidosis. Intramedullary sarcoidosis is a rare first manifestation of the disease and it can mimic an intramedullary tumor, which is often manifested with symptoms that initiate from spinal cord compression, resulting in paraparesis, sensory disorders and sphincter dysfunction. We present a case of intramedullary sarcoidosis that mimics a tumor of the thoracic spinal cord. Clinical features, neuroradiological, pathohistological findings, laboratory analysis and surgical treatment of such a rare entity are being discussed.
Vili Beros; Karlo Houra; Kresimir Rotim; Damir Kovac; Hrvoje Cupić
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Collegium antropologicum     Volume:  32     ISSN:  0350-6134     ISO Abbreviation:  Coll Antropol     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-09-01     Completed Date:  2008-09-30     Revised Date:  2009-02-04    
Medline Journal Info:
Nlm Unique ID:  8003354     Medline TA:  Coll Antropol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  645-7     Citation Subset:  IM    
Department of Neurosurgery, University Hospital Sestre milosrdnice, Zagreb, Croatia.
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MeSH Terms
Diagnosis, Differential
Magnetic Resonance Imaging
Sarcoidosis / diagnosis*
Spinal Cord Diseases / diagnosis*
Spinal Cord Neoplasms / diagnosis
Thoracic Vertebrae

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