| Thoracic duct lymph flow in pregnant sheep and response to blood volume expansion. | |
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MedLine Citation:
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PMID: 3717382 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Left thoracic duct lymph flow rate averaged 0.077 +/- 0.003 (SD) and 0.078 +/- 0.003 ml X min-1 X kg-1 in near-term pregnant and nonpregnant sheep (P greater than 0.5). Lymph and plasma protein concentrations were unaltered in the pregnant compared with the nonpregnant animals. The thoracic duct lymph flow responses to three serial intravenous infusions of lactated Ringer solution were essentially the same in the pregnant and nonpregnant animals. Blood volume and vascular pressure changes during and after volume loading were essentially the same in both groups. In addition, terbutaline administration after volume loading caused no change in thoracic duct lymph flow rates. Thus the present study suggests that basal lymph flow rates, lymphatic function, and vascular as well as interstitial compliances are largely unaltered late in pregnancy in the sheep. In addition, beta-mimetic stimulation with terbutaline does not appear to suppress lymph flow rate. |
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Authors:
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G Valenzuela; L L Woods; R A Brace |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of physiology Volume: 250 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1986 Jun |
Date Detail:
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Created Date: 1986-07-24 Completed Date: 1986-07-24 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R1095-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Proteins / metabolism Blood Volume / drug effects Compliance Extracellular Space / physiology Female Isotonic Solutions / pharmacology Lymph / drug effects, metabolism, physiology* Osmolar Concentration Plasma Substitutes / pharmacology* Pregnancy Proteins / metabolism Sheep Terbutaline / pharmacology Thoracic Duct / physiology* Vascular Resistance |
| Chemical | |
Reg. No./Substance:
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0/Blood Proteins; 0/Isotonic Solutions; 0/Plasma Substitutes; 0/Proteins; 23031-25-6/Terbutaline; 8022-63-7/Ringer's lactate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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