Document Detail

Thoracic duct lymph flow after pancreatitis: role in circulatory collapse.
MedLine Citation:
PMID:  7136949     Owner:  NLM     Status:  MEDLINE    
We examined the effects of acute hemorrhagic pancreatitis on thoracic duct lymph flow and its protein concentration. Thoracic duct lymph flow increased and the protein concentration decreased. These changes in the lymph were associated with steady decreases in arterial pressure and cardiac output and increase in systemic vascular resistance. The results suggest that the increased lymph flow and decreased protein concentration were due to either an ultrafiltration causing a dilution of the lymph protein concentration or to the heterogeneous origin of thoracic duct lymph such that redistribution of blood flow to the essential beds (eg, kidneys) after arterial hypotension altered the lymph flow and its protein concentration. The increase in filtration and the absence of a compensatory "autotransfusion" during arterial hypotension may be a mechanism contributing to circulatory shock in acute pancreatitis.
A B Malik; R J Mullins; P S Barie; D R Bell; B C Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in shock research     Volume:  8     ISSN:  0195-878X     ISO Abbreviation:  Adv Shock Res     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-18     Completed Date:  1982-12-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7908298     Medline TA:  Adv Shock Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  81-9     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Blood Pressure
Blood Proteins / analysis
Capillary Resistance
Cardiac Output
Lymph / physiology*
Lymphatic System / physiopathology*
Pancreatitis / physiopathology*
Shock, Hemorrhagic / physiopathology*
Thoracic Duct / physiopathology
Reg. No./Substance:
0/Blood Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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