Document Detail


Thomas Addis, 1881-1949, clinical scientist, hematologist and pioneering nephrologist: a brief biography.
MedLine Citation:
PMID:  20013743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thomas Addis is an important figure in the history of nephrology. Born in Scotland and trained in Edinburgh, he came to San Francisco in 1911 to the new Stanford School of Medicine to run the clinical laboratory. Over the next 38 years, he made many contributions to renal physiology, the investigation of the structure and function of the kidneys in Bright's disease, and studies of kidney growth, hypertrophy and protein metabolism. Largely forgotten today, he was one of the first to use urea clearance as a measure of kidney function and was the first to systematize examination of the urinary sediment - the Addis count. He was also a leader in the use of diet and rest in the treatment of Bright's disease. Unknown to most nephrologists, before he came to the United States during the first 6 years following his graduation, he became one of the leading clinical investigators in hematology. His special interests were the mechanism of blood clotting and hemophilia. He was the first to transfuse fresh blood into a hemophiliac patient and show that this shortened the patient's clotting time. Addis was a great, if eccentric, personality as well as a great scientist. He was beloved by his many colleagues and students and was honored in his lifetime both in the United States and Great Britain.
Authors:
Christopher R Blagg
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Publication Detail:
Type:  Biography; Historical Article; Journal Article    
Journal Detail:
Title:  Journal of nephrology     Volume:  22 Suppl 14     ISSN:  1121-8428     ISO Abbreviation:  J. Nephrol.     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9012268     Medline TA:  J Nephrol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  115-9     Citation Subset:  IM    
Affiliation:
University of Washington and Northwest Kidney Centers, Seattle, Washington 98040, USA. blaggc@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Glomerulonephritis / history
Hematology / history
History, 20th Century
Humans
Nephrology / history*
United States
Personal Name Subject
Personal Name Subject:
Thomas Addis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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