| Third trimester fetal intracranial hemorrhage owing to vitamin K deficiency associated with hyperemesis gravidarum. | |
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MedLine Citation:
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PMID: 19956025 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In rare cases, severe fetal vitamin K deficiency bleeding may occur in utero as a result of insufficient vitamin K placental transfer. We present a case of a 32-week-preterm infant born with severe intracranial hemorrhage to a pregnant woman who suffered from hyperemesis gravidarum. Neonatal hematologic status was compatible with vitamin K deficiency whereas the maternal coagulation function was normal. This case emphasizes the potential risk of fetal bleeding owing to vitamin K deficiency in pregnancies complicated with hyperemesis gravidarum. These women should be closely monitored and vitamin K prophylaxis might be considered. |
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Authors:
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Smadar Eventov-Friedman; Gil Klinger; Eric S Shinwell |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric hematology/oncology Volume: 31 ISSN: 1536-3678 ISO Abbreviation: J. Pediatr. Hematol. Oncol. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-03 Completed Date: 2010-01-07 Revised Date: 2011-10-06 |
Medline Journal Info:
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Nlm Unique ID: 9505928 Medline TA: J Pediatr Hematol Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 985-8 Citation Subset: IM |
Affiliation:
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Department of Neonatology, Kaplan Medical Center, Rehovot and Hebrew University, Jerusalem, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antifibrinolytic Agents / therapeutic use Female Fetal Diseases / etiology*, prevention & control Gestational Age Humans Hyperemesis Gravidarum / etiology*, pathology Infant, Newborn Intracranial Hemorrhages / drug therapy, etiology* Male Pregnancy Pregnancy Trimester, Third* Vitamin K / therapeutic use Vitamin K Deficiency / etiology*, prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Antifibrinolytic Agents; 12001-79-5/Vitamin K |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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