Document Detail

Thinner, smaller, faster: IR techniques to probe the functionality of biological and biomimetic systems.
MedLine Citation:
PMID:  20818765     Owner:  NLM     Status:  MEDLINE    
New techniques in vibrational spectroscopy are promising for the study of biological samples as they provide exquisite spatial and/or temporal resolution with the benefit of minimal perturbation of the system during observation. In this Minireview we showcase the power of modern infrared techniques when applied to biological and biomimetic systems. Examples will be presented on how conformational changes in peptides can be traced with femtosecond resolution and nanometer sensitivity by 2D IR spectroscopy, and how surface-enhanced infrared difference absorption spectroscopy can be used to monitor the effect of the membrane potential on a single proton-transfer step in an integral membrane protein. Vibrational spectra of monolayers of molecules at basically any interface can be recorded with sum-frequency generation, which is strictly surface-sensitive. Chemical images are recorded by applying scanning near-field infrared microscopy at lateral resolutions better than 50 nm.
Kenichi Ataka; Tilman Kottke; Joachim Heberle
Related Documents :
20366985 - Coherent anti-stokes raman holography for chemically selective single-shot nonscanning ...
15048395 - Near-infrared imaging spectroscopy (niris) and image rank analysis for remote identific...
11236875 - Time series of eit chest images using singular value decomposition and fourier transform.
8770185 - Spectral analysis of muscle fiber images as a means of assessing sarcomere heterogeneity.
23837965 - Dynamic programming in parallel boundary detection with application to ultrasound intim...
23602425 - Aggregation-induced emission of a novel conjugated phosphonium salt and its application...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  49     ISSN:  1521-3773     ISO Abbreviation:  Angew. Chem. Int. Ed. Engl.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-09-06     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  5416-24     Citation Subset:  IM    
Fachbereich Physik-Experimentelle Molekulare Biophysik, Freie Universität Berlin, Arnimallee 14, 14195 Berlin, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biomimetic Materials / chemistry
Proteins / chemistry
Spectrophotometry, Infrared / economics,  instrumentation,  methods*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  In pursuit of a competitive target: total synthesis of the antibiotic kendomycin.
Next Document:  Controlled reducibility of a metal-organic framework with coordinatively unsaturated sites for prefe...