| Thin-section chest CT findings in systemic lupus erythematosus with antiphospholipid syndrome: A comparison with systemic lupus erythematosus without antiphospholipid syndrome. | |
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MedLine Citation:
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PMID: 21501937 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To assess thin-section chest CT findings in systemic lupus erythematosus (SLE) with antiphospholipid syndrome (APS), in comparison with SLE without APS. MATERIALS AND METHODS: We retrospectively reviewed the medical records and thin-section CT findings of 17 consecutive patients with an established diagnosis of SLE with APS, comparing with 37 consecutive SLE patients without APS, between 2004 and 2008, and patients who had other autoimmune disease, such as Sjögren syndrome, were excluded. No significant differences were seen between the two groups in age, gender, smoking habits, or history of steroid pulse and biological therapy. CT images of 2mm thickness obtained with a 16- or 64-detector row CT were retrospectively evaluated by two radiologists in consensus on ultra high-resolution gray-scale monitors. RESULTS: The frequency of thin-section CT abnormalities was higher in SLE with APS group (82%) than in SLE without APS group (43%). Ground-glass opacity (59%), architectural distortion (47%), reticulation (41%), enlarged peripheral pulmonary artery (29%), and mosaic attenuation (29%) were significantly more common in the SLE with APS group than in the SLE without APS group (Fisher's exact test, p<0.01). CONCLUSION: SLE patients with APS have increased prevalence of thin-section chest CT abnormalities than those without APS. |
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Authors:
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Hodaka Oki; Takatoshi Aoki; Kazuyoshi Saito; Yoshiko Yamashita; Mai Hanamiya; Yoshiko Hayashida; Yoshiya Tanaka; Yukunori Korogi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-16 |
Journal Detail:
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Title: European journal of radiology Volume: - ISSN: 1872-7727 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Radiology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Kitakyushu 807-0804, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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