| Thin layer chromatography analysis of antioxidant constituents of lichens from Antarctica. | |
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MedLine Citation:
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PMID: 18553181 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antioxidant agents against reactive oxygen species can be used for several cosmetic and medicinal applications. Methanol-water (90:10 v/v) extracts of five polar lichen species--namely Stereocaulon alpinum Laurer (Stereocaulaceae); Ramalina terebrata Hook and Taylor (Ramalinaceae); Caloplaca sp. (Teloschistaceae); Lecanora sp. (Lecanoraceae); and Caloplaca regalis (Vain.)Zahlbr (Teloschistaceae) from King George Island (Antarctica)--were analyzed using thin layer chromatography (TLC) followed by a DPPH (2,2-diphenyl-1-picrylhydrazyl) spray technique. The experimental data showed that 33-50% of the major constituents of the test extracts were active antioxidants. Stereocaulon alpinum and R. terebrata showed a higher number (50%) of antioxidant constituents, although their activities were comparatively weak. The strength of antioxidant activity in terms of discoloration of DPPH was shown to be stronger by the constituents of S. alpinum, C. regalis and C. sp. In addition, phenolic content in these Antarctic lichen extracts was in the range of 17-47 mg/g, supporting the antioxidant data of TLC analysis. Thus, these results suggest that Antarctic lichen contains a variety of strong antioxidant constituents. Therefore, further study of the laboratory culture of lichen is warranted to investigate possible commercial production, followed by isolation and characterization of the active antioxidant agents, which can be used against various oxidative stress-related diseases. |
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Authors:
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Hari Datta Bhattarai; Babita Paudel; Soon Gyu Hong; Hong Kum Lee; Joung Han Yim |
Publication Detail:
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Type: Letter; Research Support, Non-U.S. Gov't Date: 2008-06-17 |
Journal Detail:
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Title: Journal of natural medicines Volume: 62 ISSN: 1861-0293 ISO Abbreviation: J Nat Med Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-09-10 Completed Date: 2008-11-24 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 101518405 Medline TA: J Nat Med Country: Japan |
Other Details:
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Languages: eng Pagination: 481-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antarctic Regions Antioxidants / chemistry, isolation & purification, pharmacology* Biphenyl Compounds Chromatography, Thin Layer Lichens / chemistry* Phenols / isolation & purification, pharmacology Picrates Plant Extracts / chemistry, isolation & purification, pharmacology* Reactive Oxygen Species / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Biphenyl Compounds; 0/Phenols; 0/Picrates; 0/Plant Extracts; 0/Reactive Oxygen Species; 1898-66-4/2,2-diphenyl-1-picrylhydrazyl |
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