Document Detail

Thigh muscle strength, functional capacity, and self-reported function in patients at high risk of knee osteoarthritis compared with controls.
MedLine Citation:
PMID:  20853469     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Reduced muscle strength is suggested as a risk factor for knee osteoarthritis (OA). Meniscectomy patients have an increased risk of developing knee OA. The aim of this study was to identify reductions in different aspects of muscle strength as well as objectively measured and self-reported lower extremity function in middle-aged patients who had undergone a meniscectomy compared with controls. METHODS: Thirty-one patients who had undergone surgery in 2006 and 2007 (mean ± SD age 46 ± 6 years, mean ± SD body mass index [BMI] 26 ± 4 kg/m(2), and mean ± SD postsurgery 21 ± 6 months) and 31 population-based controls (mean ± SD age 46 ± 6 years and mean ± SD BMI 26 ± 4 kg/m(2)) were examined for maximal muscle strength and rapid force capacity, distance achieved during the one-leg hop test, and the maximum number of knee bends performed in 30 seconds. The Knee Injury and Osteoarthritis Outcome Score (KOOS) was used to determine self-reported outcomes. RESULTS: No differences were detected in any muscle strength variables between the operated and nonoperated leg (mean ± SD quadriceps maximum voluntary contraction of 2.80 ± 0.10 for the operated leg and 2.88 ± 0.10 for the nonoperated leg), between patients and controls (mean ± SD torque of 2.70 ± 0.09 Nm × kg(-1) for the controls; P = 0.26 for main effect leg), or in objectively measured function (P ≥ 0.27). Patients reported 10-26 points worse KOOS scores in all 5 subscales (P < 0.001). CONCLUSION: Thigh muscle strength is not impaired in middle-aged adults 2 years after resection of a degenerative tear. Our findings indicate that factors other than muscle strength are responsible for the perceived functional limitations and suggest that training to improve strength alone may not be sufficient to improve self-reported function in patients at high risk of knee OA.
Jonas Bloch Thorlund; Per Aagaard; Ewa M Roos
Related Documents :
8818199 - Effect of a 6-week endurance training programme and branched-chain amino acid supplemen...
12074739 - Muscle strength, na,k-pumps, magnesium and potassium in patients with alcoholic liver c...
22372799 - Efficacy of an enterovaccine in recurrent episodes of diarrhea in the dog: a pilot study.
22092019 - Isolated cardiomyopathy caused by a dmd nonsense mutation in somatic mosaicism: further...
6627419 - Evaluation of isokinetic muscle performance.
21840969 - Polysialyltransferase-overexpression in schwann cells mediates different effects during...
10975719 - Experimental surgery in spinal cord lesions by connecting upper motoneurons directly to...
3957639 - Somatosensory evoked potentials to muscle percussion in humans: upper extremity.
7737309 - The inhibitory mechanisms of nicorandil in isolated rat urinary bladder and femoral art...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Arthritis care & research     Volume:  62     ISSN:  2151-4658     ISO Abbreviation:  Arthritis Care Res (Hoboken)     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-20     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101518086     Medline TA:  Arthritis Care Res (Hoboken)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1244-51     Citation Subset:  IM    
University of Southern Denmark, Odense, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Case-Control Studies
Follow-Up Studies
Matched-Pair Analysis
Menisci, Tibial / surgery*
Middle Aged
Muscle Strength / physiology
Muscle Weakness / etiology,  prevention & control*
Osteoarthritis, Knee / etiology*,  physiopathology
Physical Endurance / physiology
Postoperative Complications / etiology,  prevention & control*
Quadriceps Muscle / physiology*
Recovery of Function
Reference Values
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma.
Next Document:  Musculoskeletal pain and incident disability in community-dwelling older adults.