Document Detail

Thermoregulatory and metabolic responses following cardiac surgery.
MedLine Citation:
PMID:  8889427     Owner:  NLM     Status:  MEDLINE    
The thermoregulatory responses in 13 haemodynamically stable patients were evaluated over a 7-h period following coronary artery bypass graft surgery. Cutaneous vasoconstriction was defined by a forearm-to-fingertip skin temperature gradient (delta Tskin) > or = 4 degrees C and muscular hyperactivity was assessed by integrating the electromyographic signals (iEMG). Blood gases and lactate were measured in arterial, mixed venous and femoral venous blood. After arrival in ICU, we observed: (1) mild central hypothermia (Tc = 34.8 +/- 0.6 degrees C) and elevated peripheral vascular resistance in all the patients; (2) delta Tskin > or = 4 degrees C in 11 of 13 patients that persisted until a median Tc of 37.1 degrees C was achieved; (3) a transient increase in iEMG (+ 18%) was accompanied by an increase in total body O2 uptake (+ 28%); (4) elevated muscle O2 extraction rate (56 +/- 18% after 3 h) and lactate release. These data suggest that residual hypothermia in sedated patients after cardiac surgery elicits appropriate thermoregulatory responses that are associated with transient O2 supply/uptake mismatch within skeletal muscles.
M Licker; A Schweizer; F E Ralley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  13     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-01-31     Completed Date:  1997-01-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  502-10     Citation Subset:  IM    
Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, University Hospital Geneva, Switzerland.
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MeSH Terms
Acid-Base Equilibrium
Body Temperature
Body Temperature Regulation*
Coronary Artery Bypass*
Lactates / metabolism*
Middle Aged
Muscle, Skeletal / metabolism,  physiology
Oxygen Consumption
Skin / blood supply
Vascular Resistance
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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