Document Detail


Thermomechanical properties, collapse pressure, and expansion of shape memory polymer neurovascular stent prototypes.
MedLine Citation:
PMID:  19107804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Shape memory polymer stent prototypes were fabricated from thermoplastic polyurethane. Commercial stents are generally made of stainless steel or other alloys. These alloys are too stiff and prevent most stent designs from being able to navigate small and tortuous vessels to reach intracranial lesions. A solid tubular model and a high flexibility laser etched model are presented. The stents were tested for collapse in a pressure chamber. At 37 degrees C, the full collapse pressure was comparable to that of commercially available stents, and higher than the estimated maximum pressure exerted by intracranial arteries. However, there is a potential for onset of collapse, which needs further study. The stents were crimped and expanded, the laser-etched stent showed full recovery with an expansion ratio of 2.7 and a 1% axial shortening.
Authors:
Géraldine M Baer; Thomas S Wilson; Ward Small; Jonathan Hartman; William J Benett; Dennis L Matthews; Duncan J Maitland
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of biomedical materials research. Part B, Applied biomaterials     Volume:  90     ISSN:  1552-4981     ISO Abbreviation:  J. Biomed. Mater. Res. Part B Appl. Biomater.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-09     Completed Date:  2009-10-02     Revised Date:  2011-07-20    
Medline Journal Info:
Nlm Unique ID:  101234238     Medline TA:  J Biomed Mater Res B Appl Biomater     Country:  United States    
Other Details:
Languages:  eng     Pagination:  421-9     Citation Subset:  IM    
Copyright Information:
(c) 2008 Wiley Periodicals, Inc.
Affiliation:
Department of Biomedical Engineering, University of California Davis, Davis, California 95616, USA.
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MeSH Terms
Descriptor/Qualifier:
Models, Theoretical
Neovascularization, Physiologic*
Polymers*
Pressure
Stents*
Grant Support
ID/Acronym/Agency:
R01 EB000462-07/EB/NIBIB NIH HHS; R01EB000462/EB/NIBIB NIH HHS
Chemical
Reg. No./Substance:
0/Polymers
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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