| Thermogenic responses to high-energy phosphate contents and/or hindlimb suspension in rats. | |
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MedLine Citation:
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PMID: 8832335 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effects of chronic depletion of high-energy phosphate compounds by feeding beta-guanidinopropionic acid (beta-GPA) with or without hindlimb suspension (HS) on body temperature were studied in rats. Lower rectal and skin temperatures were observed in rats after 10 d of HS. Suspension-related enlargement of the interscapular brown adipose tissue (BAT), associated with adrenal hypertrophy, was seen. Feeding beta-GPA also caused a hypothermia and BAT enlargement. It is suggested that the hypothermic response to HS may be due to decreased contractile activity and metabolic rate in skeletal muscles, associated with stress. It is also speculated that the changes in the thermogenesis in rats fed beta-GPA might be related to a stimulated ATP synthesis with sacrificed heat production, but not associated with stress. |
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Authors:
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T Wakatsuki; F Hirata; H Ohno; M Yamamoto; Y Sato; Y Ohira |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Japanese journal of physiology Volume: 46 ISSN: 0021-521X ISO Abbreviation: Jpn. J. Physiol. Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-12-06 Completed Date: 1996-12-06 Revised Date: 2007-03-21 |
Medline Journal Info:
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Nlm Unique ID: 2985184R Medline TA: Jpn J Physiol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 171-5 Citation Subset: IM; S |
Affiliation:
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Department of Physiology and Biomechanics, National Institute of Fitness and Sports, Kanoya, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Temperature / physiology* Body Temperature Regulation / physiology* Body Weight / physiology Energy Metabolism / physiology* Guanidines / pharmacology Hindlimb / physiology* Male Phosphates / metabolism* Propionic Acids / pharmacology Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Guanidines; 0/Phosphates; 0/Propionic Acids; 353-09-3/guanidinopropionic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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