Document Detail

Thermogenic responses to graded doses of noradrenaline in undernourished Indian male subjects.
MedLine Citation:
PMID:  2706225     Owner:  NLM     Status:  MEDLINE    
1. Seventeen male subjects with an energy intake of 10.6 (SD 1.7) MJ/d and ten male undernourished labourers with an energy intake of 8.0 (SD 1.2) MJ/d were studied. The controls were subdivided into ten underweight controls with a body mass index (weight/height2; BMI) less than 18 (17.2 (SD 0.9)) and seven normal-weight controls with a BMI greater than 20 (21.3 (SD 1.6)), while the undernourished labourers had a BMI less than 18 (16.8 (SD 1.2)). 2. Comparison of thermogenic responses to increasing doses of noradrenaline showed no overall significant inter-group differences when subjected to a nested analysis of variance (ANOVA). For the initial doses of 0.05 and 0.1 micrograms noradrenaline, significantly lower responses were seen in the undernourished subjects, while the highest dose showed comparable responses in all three groups. Thermogenic responses to the initial two doses, when corrected for fat-free mass (FFM) differences, were 40% lower in the undernourished group when compared with the underweight group with similar BMI and FFM values. However, this finding was not statistically significant. 3. The basal oxygen consumption of the undernourished group, expressed per unit FFM, was significantly higher than that of the controls.
A V Kurpad; R N Kulkarni; M L Sheela; P S Shetty
Related Documents :
23613695 - Is high-dose aspirin necessary in the acute phase of kawasaki disease?
23172265 - Evaluation of a pediatric continuous-infusion vancomycin therapy guideline.
24383595 - Successful treatment using high-dose intravenous immunoglobulin in a patient with rapid...
17063625 - The effect of magnesium supplementation on lactate levels of sportsmen and sedanter.
11835235 - Thyroidal uptake and radiation dose after repetitive i-131-mibg treatments: influence o...
17589845 - Phase i study of the combination of nedaplatin and weekly paclitaxel in patients with a...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of nutrition     Volume:  61     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-06-07     Completed Date:  1989-06-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  201-8     Citation Subset:  IM    
Department of Physiology, St John's Medical College, Bangalore, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Dose-Response Relationship, Drug
Energy Intake*
Energy Metabolism / drug effects
Norepinephrine / administration & dosage,  pharmacology*
Oxygen Consumption / drug effects*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Changes in energy expenditure during the menstrual cycle.
Next Document:  Liver function in protein-energy malnutrition measured by cinnamic acid tolerance and benzoic acid t...