Document Detail

Thermodilution left-sided cardiac output for valve area determination after balloon mitral valvotomy.
MedLine Citation:
PMID:  7942487     Owner:  NLM     Status:  MEDLINE    
This study was conducted to establish the validity of left-sided cardiac output measurement with a Swan-Ganz catheter and assess its accuracy in estimating mitral valve area (MVA) by the Gorlin formula. The use of right-sided cardiac output after balloon mitral valvotomy (BMV) can give inaccurate measurements for Gorlin-derived MVA because of the atrial septal defect (ASD) created during the procedure. The left-sided cardiac output was measured with a Swan-Ganz catheter (proximal port in the left atrium and then in the left ventricle, and distal port in the ascending aorta) in 10 consecutive patients before and after BMV. Gorlin-derived MVA cardiac output by this method was compared with (1) Gorlin-derived MVA by means of right-sided cardiac output with and without balloon occlusion of the ASD and (2) MVA measured by echocardiography. Before BMV, a close agreement with a good correlation between left-sided and right-sided cardiac output was found (r = 0.83, p = 0.006). Furthermore, Gorlin-derived MVA by cardiac output with either method was comparable with valve area by echo. After BMV, left-sided cardiac output correlated well (r = 0.92, p = 0.0002) and was comparable with right-sided cardiac output with occlusion of the ASD (mean difference 0.17 +/- 0.49 L/min, p = 0.3) but was significantly lower than the value obtained with open ASD (mean difference 0.93 +/- 0.77 L/min, p = 0.004). Comparison of the correspondent MVAs yielded similar results. Gorlin-derived MVA with left-sided cardiac output and MVA by echo were also similar.(ABSTRACT TRUNCATED AT 250 WORDS)
H Gamra; H P Zhang; R A Clugston; P Whittaker; J W Allen; F Y Lau; C E Ruiz
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  128     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1994-11-18     Completed Date:  1994-11-18     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  934-40     Citation Subset:  AIM; IM    
Department of Cardiology, Loma Linda University Medical Center, CA 92354-0200.
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MeSH Terms
Balloon Dilatation*
Cardiac Output / physiology*
Catheterization, Swan-Ganz*
Echocardiography, Doppler
Feasibility Studies
Middle Aged
Mitral Valve / physiopathology,  ultrasonography
Mitral Valve Stenosis / diagnosis,  physiopathology,  therapy*
Regression Analysis
Reproducibility of Results
Thermodilution / instrumentation,  methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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