Document Detail

Thermic effect of medium-chain and long-chain triglycerides in man.
MedLine Citation:
PMID:  3532757     Owner:  NLM     Status:  MEDLINE    
The thermic effects of 400 kcal meals of medium-chain triglycerides (MCT) and long-chain triglycerides (LCT) were compared in seven healthy men. Metabolic rate was measured before the meals and for 6 h after the meals by indirect calorimetry. Mean postprandial oxygen consumption was 12% higher than basal oxygen consumption after the MCT meal but was only 4% higher than the basal oxygen consumption after the LCT meal. There was a 25-fold increase in plasma beta-hydroxybutyrate concentration and a slight increase in serum insulin concentration after MCT ingestion but not after LCT ingestion. Plasma triglyceride concentrations increased 68% after the LCT meal and did not change after the MCT meal. These data raise the possibility that long-term substitution of MCT for LCT would produce weight loss if energy intake remained constant.
T B Seaton; S L Welle; M K Warenko; R G Campbell
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  44     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-11-20     Completed Date:  1986-11-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  630-4     Citation Subset:  AIM; IM    
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MeSH Terms
3-Hydroxybutyric Acid
Body Temperature Regulation / drug effects*
Calorimetry, Indirect
Dietary Fats / pharmacology*
Energy Metabolism / drug effects*
Glycerol / blood
Hydroxybutyrates / blood
Insulin / blood
Oxygen Consumption / drug effects
Triglycerides / blood,  pharmacology*
Grant Support
Reg. No./Substance:
0/Dietary Fats; 0/Hydroxybutyrates; 0/Triglycerides; 11061-68-0/Insulin; 300-85-6/3-Hydroxybutyric Acid; 56-81-5/Glycerol

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