| Thermal balloon angioplasty in a canine model: preliminary results. | |
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MedLine Citation:
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PMID: 2151968 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preliminary results suggest that thermal balloon angioplasty (BA) may produce plaque welding, decreased elastic recoil, and increased luminal caliber. The authors report results of a simple method of thermal BA in a canine model. Seven mongrel dogs (15-25 kg) underwent conventional BA of each iliac artery with balloons that were 1-2 mm larger than the vessel lumen. The balloons were then perfused with a mixture of saline and contrast material at either 25 degrees C (control) or 100 degrees C for 1 minute. Compared with baseline measurements, thermal BA produced greater lumen enlargement (+16.7%) than control BA (+3.4%) immediately after the procedure (P less than .05). This trend persisted in vessels studied after a delay of 2, 4, or 12 weeks. Histologic sections from specimens studied after a delay demonstrated intimal hyperplasia in both the thermally treated and control arteries. Medial sclerosis was consistently seen in the thermally treated arteries. The authors conclude that thermal BA results in immediate and delayed increases in arterial diameter compared with conventional BA due to decreased elastic recoil and medial sclerosis. |
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Authors:
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T Gleason; A H Cragg; T P Smith; S K Landas; S C De Jong |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of vascular and interventional radiology : JVIR Volume: 1 ISSN: 1051-0443 ISO Abbreviation: J Vasc Interv Radiol Publication Date: 1990 Nov |
Date Detail:
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Created Date: 1992-04-16 Completed Date: 1992-04-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203369 Medline TA: J Vasc Interv Radiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 121-6 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City 52242. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Balloon
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instrumentation* Animals Dogs Evaluation Studies as Topic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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